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Article

A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis.

Molecular oncology - 1 Jun 2020

Gonçalves Céline S, Xavier-Magalhães Ana, Martins Eduarda P, Pinto Afonso A, Pires Manuel Melo, Pinheiro Célia, Reis Rui M, Sousa Nuno, Costa Bruno M

Abstract excerpt

Despite much effort to improve treatments, patients with malignant glioma still present a very poor prognosis that has not changed significantly in the last decades. In this context, it is crucial to better understand glioma pathogenesis to identify new molecular prognostic subgroups and therapeutic targets. WNT6 was recently identified as a new oncogenic molecule in glioblastoma (GBM), with prognostic value in...

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Source

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Identifiers

PMID: 31923345
DOI: 10.1002/1878-0261.12633
PMCID: PMC7266278

Genes

WNT6
HOXA9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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