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Article

A novel mutation in GPD1‑L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents.

International journal of molecular medicine - 1 Mar 2020

Fan Jun, Ji Cheng-Cheng, Cheng Yun-Jiu, Yao Hao, Chen Xu-Miao, Zheng Zi-Heng, Wu Su-Hua

Abstract excerpt

Early repolarization syndrome (ERS) is associated with genetic mutations, but the role of the glycerol‑3‑phosphate dehydrogenase 1‑like (GPD1‑L) mutation remains unclear. The aim of the present study was to investigate the role and potential underlying mechanism of GPD1‑L mutation P112L in the pathogenesis of ERS. Whole‑genome sequencing was performed on samples from a family with ERS, and the gene sequencing...

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Identifiers

PMID: 31922248
DOI: 10.3892/ijmm.2020.4454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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