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Article

Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome.

Circulation - 13 Nov 2007

Van Norstrand David W, Valdivia Carmen R, Tester David J, Ueda Kazuo, London Barry, Makielski Jonathan C, Ackerman Michael J

Abstract excerpt

BACKGROUND: Autopsy-negative sudden unexplained death, including sudden infant death syndrome, can be caused by cardiac channelopathies such as Brugada syndrome (BrS). Type 1 BrS, caused by mutations in the SCN5A-encoded sodium channel, accounts for approximately 20% of BrS. Recently, a novel mutation in the glycerol-3-phosphate dehydrogenase 1-like gene (GPD1-L) disrupted trafficking of SCN5A in a...

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Identifiers

PMID: 17967976
DOI: 10.1161/CIRCULATIONAHA.107.704627
PMCID: PMC3332545

Genes

GPD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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