Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autophagy is essential for oligodendrocyte differentiation, survival, and proper myelination

4 Jun 2019

Abstract excerpt

Abstract Deficient myelination, the spiral wrapping of highly specialized membrane around axons, causes severe neurological disorders. Maturation of oligodendrocyte progenitor cells (OPC) to myelinating oligodendrocytes (OL), the sole providers of central nervous system (CNS) myelin, is tightly regulated and involves extensive morphological changes. Here, we present evidence that autophagy, the targeted isolation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to MicroRNA in disease regulation
Share to Neurogenesis and neuroplasticity mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31162728
DOI: 10.1002/glia.23646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagy is essential for oligodendrocyte differentiation, survival, and proper myelinationPMID 31162728Read ↗

Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent MannerSemantic proximity Read ↗

Disruption of Oligodendroglial Autophagy Leads to Myelin Morphological Deficits, Neuronal Apoptosis, and Cognitive Decline in Aged MiceSemantic proximity Read ↗

Mechanisms of neuronal homeostasis: Autophagy in the axon.Semantic proximity Read ↗

Autophagy collaborates with apoptosis pathways to control oligodendrocyte numberSemantic proximity Read ↗

BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytesSemantic proximity Read ↗

Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and deathSemantic proximity Read ↗

Towards a better understanding of the neuro-developmental role of autophagy in sickness and in healthSemantic proximity Read ↗

Autophagy promotes oligodendrocyte survival and function following dysmyelination in a long-lived myelin mutant.Semantic proximity Read ↗

How autophagy is related to programmed cell death during the development of the nervous systemSemantic proximity Read ↗

Emerging Role of the Autophagy/Lysosomal Degradative Pathway in Neurodevelopmental Disorders With EpilepsySemantic proximity Read ↗

Neuronal autophagy: Going the distance to the axonSemantic proximity Read ↗

Beyond Support Cells: Astrocytic Autophagy as a Central Regulator of CNS Homeostasis and Neurodegenerative DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.