Article
Analysis of the DOK1 gene in breast cancer.
Molecular biology reports - 1 Mar 2020
Tuna Esin, Ersoy Yeliz Emine, Bulut Pelin, Ozdemir Filiz, Buyru Nur
Abstract excerpt
Breast cancer, which is the most common type of cancer among women, is a heterogenous disease. It results from progressive accumulation of genetic and epigenetic alterations in different genes. The Dok1 protein has been identified as the major substrate of protein tyrosine kinases in hematopoietic cells. It is considered as a tumor suppressor due to the reports which describe its inhibitory effect on major...
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