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Article

Roles of Fibulin-2 in Carcinogenesis

9 Jan 2020

Abstract excerpt

Fibulin-2, an extracellular matrix (ECM) protein expressed in normal epithelia, is a kind of fibulin which is associated with basement membranes (BM) and elastic ECM fibers. The role of fibulin-2 has been recognized as an oncogene. The upregulation of fibulin-2 correlates with cancer development and progression. Furthermore, the upregulation of fibulin has been detected in ovarian cancer and stomach...

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PMID: 31915327
DOI: 10.12659/msm.918099

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