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Article

Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation.

Journal of biomedical science - 6 Jan 2020

Hung Su-Jhen, Hsu Yin-Mei, Huang Sheng-Wen, Tsai Huey-Pin, Lee Leo Yi Yang, Hurt Aeron C, Barr Ian G, Shih Shin-Ru, Wang Jen-Ren

Abstract excerpt

BACKGROUND: Influenza A viruses cause epidemics/severe pandemics that pose a great global health threat. Among eight viral RNA segments, the multiple functions of nucleoprotein (NP) play important roles in viral replication and transcription. METHODS: To understand how NP contributes to the virus evolution, we analyzed the NP gene of H3N2 viruses in Taiwan and 14,220 NP sequences collected from Influenza Research...

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Identifiers

PMID: 31906961
DOI: 10.1186/s12929-019-0612-z
PMCID: PMC6943894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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