Plasma proteomic analysis of autoimmune hepatitis in an improved AIH mouse model

Abstract excerpt

BACKGROUND: The prevalence of autoimmune hepatitis (AIH) is increasing, and its early clinical diagnosis is difficult. The pathogenesis of AIH remains unclear, and AIH-related studies are largely limited because of lack of suitable mouse models. METHODS: To obtain a good tool for research on AIH, we first established an improved immune-mediated mouse model that can mimic the pathological process of AIH as in the...

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