Article
A human minisatellite hosts an alternative transcription start site for NPRL3 driving its expression in a repeat number-dependent manner.
Human mutation - 1 Apr 2020
Bertuzzi Maria, Tang Dave, Calligaris Raffaella, Vlachouli Christina, Finaurini Sara, Sanges Remo, Goldwurm Stefano, Catalan Mauro, Antonutti Lucia, Manganotti Paolo, Pizzolato Gilberto, Pezzoli Gianni, Persichetti Francesca, Carninci Piero, Gustincich Stefano
Abstract excerpt
Minisatellites, also called variable number of tandem repeats (VNTRs), are a class of repetitive elements that may affect gene expression at multiple levels and have been correlated to disease. Their identification and role as expression quantitative trait loci (eQTL) have been limited by their absence in comparative genomic hybridization and single nucleotide polymorphisms arrays. By taking advantage of cap...
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