Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases.

doi:10.1111/jgh.14968

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Article

Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases.

Journal of gastroenterology and hepatology - 1 Aug 2020

Daijo Kana, Nakahara Takashi, Inagaki Yuki, Nanba Maiko, Nishida Yuno, Uchikawa Shinsuke, Kodama Kenichiro, Oya Kazuki, Morio Kei, Fujino Hatsue, Ono Atsushi, Murakami Eisuke, Yamauchi Masami, Kawaoka Tomokazu, Miki Daiki, Tsuge Masataka, Hiramatsu Akira, Hayes C Nelson, Imamura Michio, Aikata Hiroshi, Ochi Hidenori, Chayama Kazuaki

Abstract excerpt

BACKGROUND AND AIM: The most important prognostic factor for non-alcoholic steatohepatitis (NASH) is liver fibrosis. The aim of this study is to examine clinical parameters involved in pathological progression in NASH patients who underwent repeated liver biopsy and to analyze the response to treatment with respect to NASH-related single nucleotide polymorphisms (SNPs). We performed longitudinal analysis of...

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PMID: 31896166
DOI: 10.1111/jgh.14968

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