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Pathobionts in the tumour microbiota predict survival following resection for colorectal cancer

8 May 2023

Abstract excerpt

Abstract Background and aims The gut microbiota is implicated in the pathogenesis of colorectal cancer (CRC). We aimed to map the CRC mucosal microbiota and metabolome and define the influence of the tumoral microbiota on oncological outcomes. Methods A multicentre, prospective observational study was conducted of CRC patients undergoing primary surgical resection in the UK (n = 74) and Czech Republic (n = 61)....

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PMID: 37158960
DOI: 10.1186/s40168-023-01518-w

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