Article
Testing the role of intraflagellar transport in flagellar length control using length-altering mutants of Chlamydomonas.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 17 Feb 2020
Wemmer Kimberly, Ludington William, Marshall Wallace F
Abstract excerpt
Cilia and flagella are ideal model organelles in which to study the general question of organelle size control. Flagellar microtubules are steady-state structures whose size is set by the balance of assembly and disassembly. Assembly requires intraflagellar transport (IFT), and measurements of IFT have shown that the rate of entry of IFT particles into the flagellum is a decreasing function of length. It has been...
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