Article
The Use of Whole Exome Sequencing in a Cohort of Transgender Individuals to Identify Rare Genetic Variants.
Scientific reports - 27 Dec 2019
Theisen J Graham, Sundaram Viji, Filchak Mary S, Chorich Lynn P, Sullivan Megan E, Knight James, Kim Hyung-Goo, Layman Lawrence C
Abstract excerpt
Approximately 0.5-1.4% of natal males and 0.2-0.3% of natal females meet DSM-5 criteria for gender dysphoria, with many of these individuals self-describing as transgender men or women. Despite recent improvements both in social acceptance of transgender individuals as well as access to gender affirming therapy, progress in both areas has been hampered by poor understanding of the etiology of gender dysphoria....
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