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Lyse-Reseal Erythrocytes for Transfection of Plasmodium falciparum

27 Dec 2019

Abstract excerpt

Simple and efficient transfection methods for genetic manipulation of Plasmodium falciparum are desirable to identify, characterize and validate the genes with therapeutic potential and better understand parasite biology. Among the available transfection techniques for P. falciparum, electroporation-based methods, particularly electroporation of ring-infected RBCs is routinely used. Nonetheless, transfection of...

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PMID: 31882761
DOI: 10.1038/s41598-019-56513-9

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