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Article

Arabidopsis EDR1 Protein Kinase Regulates the Association of EDS1 and PAD4 to Inhibit Cell Death.

Molecular plant-microbe interactions : MPMI - 1 Apr 2020

Neubauer Matthew, Serrano Irene, Rodibaugh Natalie, Bhandari Deepak D, Bautor Jaqueline, Parker Jane E, Innes Roger W

Abstract excerpt

ENHANCED DISEASE SUSCEPTIBILITY1 (EDS1) and PHYTOALEXIN DEFICIENT4 (PAD4) are sequence-related lipase-like proteins that function as a complex to regulate defense responses in Arabidopsis by both salicylic acid-dependent and independent pathways. Here, we describe a gain-of-function mutation in PAD4 (S135F) that enhances resistance and cell death in response to infection by the powdery mildew pathogen...

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Source

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Identifiers

PMID: 31876224
DOI: 10.1094/MPMI-12-19-0339-R
PMCID: PMC8162682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Arabidopsis EDR1 Protein Kinase Regulates the Association of EDS1 and PAD4 to Inhibit Cell Death.PMID 31876224Read ↗

Arabidopsis ENHANCED DISEASE RESISTANCE1 Protein Kinase Regulates the Association of ENHANCED DISEASE SUSCEPTIBILITY1 and PHYTOALEXIN DEFICIENT4 to Inhibit Cell DeathSemantic proximity Read ↗

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EDR2 negatively regulates salicylic acid-based defenses and cell death during powdery mildew infections of Arabidopsis thaliana.Semantic proximity Read ↗

ENHANCED DISEASE RESISTANCE4 associates with CLATHRIN HEAVY CHAIN2 and modulates plant immunity by regulating relocation of EDR1 in Arabidopsis.Semantic proximity Read ↗

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TIR signaling promotes the interactions between EDS1/PAD4 and ADR1-L1 and oligomerization of ADR1-L1Semantic proximity Read ↗

The atypical resistance gene, RPW8, recruits components of basal defence for powdery mildew resistance in Arabidopsis.Semantic proximity Read ↗

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