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Article

EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases.

Proceedings of the National Academy of Sciences of the United States of America - 16 Mar 1999

Falk A, Feys B J, Frost L N, Jones J D, Daniels M J, Parker J E

Abstract excerpt

A major class of plant disease resistance (R) genes encodes leucine-rich-repeat proteins that possess a nucleotide binding site and amino-terminal similarity to the cytoplasmic domains of the Drosophila Toll and human IL-1 receptors. In Arabidopsis thaliana, EDS1 is indispensable for the function of these R genes. The EDS1 gene was cloned by targeted transposon tagging and found to encode a protein that has...

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Identifiers

PMID: 10077677
DOI: 10.1073/pnas.96.6.3292
PMCID: PMC15935

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