Article
Omadacycline Efficacy against Enterococcus faecalis Isolated in China: In Vitro Activity, Heteroresistance, and Resistance Mechanisms.
Antimicrobial agents and chemotherapy - 21 Feb 2020
Lin Zhiwei, Pu Zhangya, Xu Guangjian, Bai Bing, Chen Zhong, Sun Xiang, Zheng Jinxin, Li Peiyu, Qu Di, Deng Qiwen, Yu Zhijian
Abstract excerpt
This study aimed to evaluate the in vitro antimicrobial activity, heteroresistance emergence, and resistance mechanism of omadacycline (OMC) in clinical Enterococcus faecalis isolates from China. A total of 276 isolates were collected retrospectively in China from 2011 to 2015. The MICs of OMC, doxycycline (DOX), and minocycline (MIN) against E. faecalis were determined by broth microdilution. Tetracycline...
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