Article
Disruption of l-Rhamnose Biosynthesis Results in Severe Growth Defects in Streptococcus mutans.
Journal of bacteriology - 25 Feb 2020
Bischer Andrew P, Kovacs Christopher J, Faustoferri Roberta C, Quivey Robert G
Abstract excerpt
The rhamnose-glucose cell wall polysaccharide (RGP) of Streptococcus mutans plays a significant role in cell division, virulence, and stress protection. Prior studies examined function of the RGP using strains carrying deletions in the machinery involved in RGP assembly. In this study, we explored loss of the substrate for RGP, l-rhamnose, via deletion of rmlD (encoding the protein responsible for the terminal...
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