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MicroRNA-21-5p participates in IgA nephropathy by driving T helper cell polarization

20 Dec 2019

Abstract excerpt

Previous studies have revealed abnormal lymphocyte subsets in IgA nephropathy (IgAN). Some microRNAs have been reported to influence T helper differentiation. Here, we explored the underlying mechanism regarding how miRNAs regulate lymphocyte subsets in IgAN. First, miRNA and mRNA profiles in PBMCs from IgAN patients and controls were obtained by next-generation sequencing and gene expression array. The target...

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PMID: 31863364
DOI: 10.1007/s40620-019-00682-3

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