Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease.

doi:10.1200/JCO.19.03011

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Article

Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Apr 2020

Hourigan Christopher S, Dillon Laura W, Gui Gege, Logan Brent R, Fei Mingwei, Ghannam Jack, Li Yuesheng, Licon Abel, Alyea Edwin P, Bashey Asad, Deeg H Joachim, Devine Steven M, Fernandez Hugo F, Giralt Sergio, Hamadani Mehdi, Howard Alan, Maziarz Richard T, Porter David L, Scott Bart L, Warlick Erica D, Pasquini Marcelo C, Horwitz Mitchell E

Abstract excerpt

PURPOSE: Patients with acute myeloid leukemia (AML) in remission remain at risk for relapse even after allogeneic hematopoietic cell transplantation (alloHCT). AML measurable residual disease (MRD) status before alloHCT has been shown to be prognostic. Whether modulation of the intensity of the alloHCT conditioning regimen in patients with AML who test positive for MRD can prevent relapse and improve survival is...

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PMID: 31860405
DOI: 10.1200/JCO.19.03011
PMCID: PMC7164487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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