Article
Sofosbuvir-containing regimens are safe and effective in the treatment of HCV patients with moderate to severe renal impairment.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2020
Eletreby Rasha, El-Serafy Magdy, Anees Mahmoud, Kasem Gamal, Salama Marwa, Elkhouly Reham, Hamdy Mostafa, Abdel Haleem Hisham, Kamal Ehab, Abdel-Razek Wael, Salama Rabab, Elshenawy Mohamed, Shafeek Ayman, Hassany Mohamed, El-Sayed Manal H, El-Shazly Yehia, Esmat Gamal
Abstract excerpt
BACKGROUND AND AIMS: This study aimed to assess the safety and efficacy of sofosbuvir (SOF)-based regimens in patients with moderate to severe renal impairment; a subject which has been questioned by many investigators with conflicting results. METHODS: This is a real-life multicentre retrospective cohort study on 4944 chronic Hepatitis C virus (HCV) patients with chronic kidney disease (CKD) (eGFR...
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