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Article

Assessing safety and efficacy of sofosbuvir for the treatment of hepatitis C.

Expert opinion on drug safety - 1 Mar 2015

D'Ambrosio Roberta, Aghemo Alessio, Colombo Massimo

Abstract excerpt

INTRODUCTION: IFN-free regimens with direct antiviral agents (DAAs) against hepatitis C virus (HCV) are likely to greatly expand patients' access and response to hepatitis C therapy, while safety and tolerability of treatments seem substantially improved. Sofosbuvir (SOF), a NS5B nucleotide polymerase inhibitor with pan-genotypic activity and a high-barrier to resistance, has been approved by FDA and EMA in an...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25645644
DOI: 10.1517/14740338.2015.1009035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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