Article
On the Nature of Monozygotic Twin Concordance and Discordance for Autistic Trait Severity: A Quantitative Analysis.
Behavior genetics - 1 Jul 2020
Castelbaum Lauren, Sylvester Chad M, Zhang Yi, Yu Qiongru, Constantino John N
Abstract excerpt
The characterizing features of autism spectrum disorder (ASD) are continuously distributed in nature; however, prior twin studies have not systematically incorporated this knowledge into estimations of concordance and discordance. We conducted a quantitative analysis of twin-twin similarity for autistic trait severity in three existing data sets involving 366 pairs of uniformly-phenotyped monozygotic (MZ) twins...
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