Article
Genetic heritability and shared environmental factors among twin pairs with autism.
Archives of general psychiatry - 1 Nov 2011
Hallmayer Joachim, Cleveland Sue, Torres Andrea, Phillips Jennifer, Cohen Brianne, Torigoe Tiffany, Miller Janet, Fedele Angie, Collins Jack, Smith Karen, Lotspeich Linda, Croen Lisa A, Ozonoff Sally, Lajonchere Clara, Grether Judith K, Risch Neil
Abstract excerpt
CONTEXT: Autism is considered the most heritable of neurodevelopmental disorders, mainly because of the large difference in concordance rates between monozygotic and dizygotic twins. OBJECTIVE: To provide rigorous quantitative estimates of genetic heritability of autism and the effects of shared environment. DESIGN, SETTING, AND PARTICIPANTS: Twin pairs with at least 1 twin with an autism spectrum disorder (ASD)...
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