Article
A broader phenotype of autism: the clinical spectrum in twins.
Journal of child psychology and psychiatry, and allied disciplines - 1 Oct 1996
Le Couteur A, Bailey A, Goode S, Pickles A, Robertson S, Gottesman I, Rutter M
Abstract excerpt
The diagnostic boundaries of the behavioural phenotype for autism were examined in 28 MZ pairs and 20 DZ same-sex twin pairs, where one or both twins had autism. In the non-autistic cotwin (i.e. in twin pairs discordant for autism) it was common to find language impairments in childhood and social deficits persisting into adulthood. Concordance for this broader phenotype was much greater in MZ pairs than DZ...
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