Article
Multiple novel hepatocellular carcinoma signature genes are commonly controlled by the master pluripotency factor OCT4
17 Dec 2019
Abstract excerpt
BACKGROUND: Worldwide, hepatocellular carcinoma (HCC) is a common solid tumor with a poor prognosis. HCC is often due to hepatitis B virus (HBV) infection. As yet, efficacious HCC treatment regimens for late-stage HCC patients are lacking. Therefore, the identification of more specific and sensitive biomarkers for its early diagnosis and treatment remains an urgent need. METHODS: Total RNAs from paired...
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