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Article

Allogeneic HSCT for adult-onset leukoencephalopathy with spheroids and pigmented glia.

Brain : a journal of neurology - 1 Feb 2020

Gelfand Jeffrey M, Greenfield Ariele L, Barkovich Matthew, Mendelsohn Bryce A, Van Haren Keith, Hess Christopher P, Mannis Gabriel N

Abstract excerpt

Adult-onset leukoencephalopathy with spheroids and pigmented glia (ALSP) is an autosomal dominant leukoencephalopathy caused by mutations in colony stimulating factor 1 receptor (CSF1R). Here we report clinical and imaging outcomes following allogeneic haematopoietic stem cell transplantation (HSCT) in two patients with ALSP at the University of California, San Francisco between January 2016 and December 2017....

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Source

Identifiers

PMID: 31840744
DOI: 10.1093/brain/awz390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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