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Article

Association of CYP2C19*2 polymorphism with clopidogrel resistance among patients with high cardiovascular risk in Northeastern Mexico.

Archivos de cardiologia de Mexico - 1 Jan 2019

Cedillo-Salazar Félix R, Martínez-Jacobo Lizeth, Pérez-Páramo Yadira X, Cerda-Flores Ricardo, Martínez Laura E, Jaime-Pérez José C, Moreno-Treviño María G, Pérez-Rodríguez Edelmiro, Bosques-Padilla Francisco J, Cedillo-Avila Montserrat, Cedillo-Avila María A, Zamudio-Osuna Michelle

Abstract excerpt

Objective: Oral antiplatelet drugs are a key to modern pharmacotherapy in cardiovascular atherothrombotic diseases. Clopidogrel (CLO) constitutes the main preventive treatment of atherothrombosis. However, a considerable inter-individual variation in CLO response has been documented, resulting in suboptimal therapy and an increased risk of recurrent adverse effects in some patients. The enzyme CYP2C19 has been...

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Identifiers

PMID: 31834317
DOI: 10.24875/ACM.19000033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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