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Article

Prevalence of CYP2C9 and CYP2C19 variants and the impact on clopidogrel efficacy in patients having CYPC19*2 variant.

Indian journal of pharmacology - 1 Jan 2000

Mehta Meha P, Gajjar Normi D, Patel Rutvi J, Joshi Lipi P, Shah Gaurang B

Abstract excerpt

OBJECTIVE: Human cytochrome p450 enzymes play an important role in the metabolism of various substances. The CYP2C subfamily consists of various important drug-metabolizing enzymes such as CYP2C9 and CYP2C19. The objectives of the study include the determination of the frequency of genetic variants (CYP2C9*2, CYP2C9*3, and CYP2C19*2) of selected enzymes using allele-specific polymerase chain reaction (ASPCR) and...

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Aryl Hydrocarbon Hydroxylases
Clopidogrel
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2C9
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Platelet Aggregation Inhibitors

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Open in PubMed Open full text

Identifiers

PMID: 36960518
DOI: 10.4103/ijp.ijp_706_22
PMCID: PMC10204895

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