A versatile cis-acting element reporter system to study the function, maturation and stability of ribosomal RNA mutants in archaea.

Abstract excerpt

General molecular principles of ribosome biogenesis have been well explored in bacteria and eukaryotes. Collectively, these studies have revealed important functional differences and few similarities between these processes. Phylogenetic studies suggest that the information processing machineries from archaea and eukaryotes are evolutionary more closely related than their bacterial counterparts. These...

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