Article
Multiomics-Based Colorectal Cancer Molecular Subtyping Using Local Scaling Network Fusion.
Journal of computational biology : a journal of computational molecular cell biology - 1 Aug 2020
Duan Xin, Wang Kejun, Ke Jia, Lan Ping, Gao Feng, Wu Xiaojian
Abstract excerpt
Colorectal cancer (CRC) is a heterogeneous disease with distinct molecular properties. Tremendous works for CRC molecular subtyping are mainly based on gene expression profiling, which cannot capture the complementary information from other data types. Based on the classical multiomics data integration method similarity network fusion (SNF), which, however, suffers the trivial parameters setting, we developed...
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