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Article

PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling

1 Dec 2019

Abstract excerpt

PD-L1 is a well-known immune co-stimulatory molecule that regulates tumour cell escape from immunity by suppressing the immune response. However, the clinical significance of PD-L1 in the progression of ovarian cancer is unclear. Our study demonstrated that PD-L1 is up-regulated in ovarian tumour tissue compared with its expression level in adjacent normal tissue. Furthermore, we confirmed that PD-L1 increases...

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PMID: 31799599
DOI: 10.1042/bsr20191041

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