Article
Transmission dynamics and control of multidrug-resistant Klebsiella pneumoniae in neonates in a developing country.
eLife - 3 Dec 2019
Crellen Thomas, Turner Paul, Pol Sreymom, Baker Stephen, Nguyen Thi Nguyen To, Stoesser Nicole, Day Nicholas Pj, Turner Claudia, Cooper Ben S
Abstract excerpt
Multidrug-resistant Klebsiella pneumoniae is an increasing cause of infant mortality in developing countries. We aimed to develop a quantitative understanding of the drivers of this epidemic by estimating the effects of antibiotics on nosocomial transmission risk, comparing competing hypotheses about mechanisms of spread, and quantifying the impact of potential interventions. Using a sequence of dynamic models,...
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