Article
Substitution 3A protein of foot-and-mouth disease virus of attenuated ZB strain rescued the viral replication and infection in bovine cells.
Research in veterinary science - 1 Feb 2020
Gao Huafeng, Wang Jihua, Zhao Guohong, Zhu Mingwang, He Yuwen, Xin Aiguo
Abstract excerpt
The non-structural protein 3A of foot-and-mouth disease virus (FMDV) plays an important role in viral replication, virulence and determination of host range. Previously we identified genomic changes in gene encoding 3A protein between the attenuated ZBatt strain and its parental virulent strain during the attenuation process. However, the effects of changes in 3A protein on viral replication and infection of the...
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