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Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival

7 Nov 2019

Abstract excerpt

Copper has been revealed to negatively affect the hematopoietic system, which has an important function in immune pathogen defense, but little is known about the potential mechanism. In this study, copper stressed larvae exhibited significantly increased mortality as well as reduced percentages of GFP-labelled macrophages and neutrophils after Aeromonas hydrophila (A. hydrophila) infection. However, those...

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PMID: 31787979
DOI: 10.3389/fimmu.2019.02599

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