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Article

Immunomodulatory Effects of Genetic Alterations Affecting the Kynurenine Pathway.

Frontiers in immunology - 1 Jan 2019

Boros Fanni A, Vécsei László

Abstract excerpt

Several enzymes and metabolites of the kynurenine pathway (KP) have immunomodulatory effects. Modulation of the activities and levels of these molecules might be of particular importance under disease conditions when the amelioration of overreacting immune responses is desired. Results obtained by the use of animal and tissue culture models indicate that by eliminating or decreasing activities of key enzymes of...

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Identifiers

PMID: 31781097
DOI: 10.3389/fimmu.2019.02570
PMCID: PMC6851023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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