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Article

The effects of placental long noncoding RNA H19 polymorphisms and promoter methylation on H19 expression in association with preeclampsia susceptibility.

IUBMB life - 1 Mar 2020

Harati-Sadegh Mahdiyeh, Kohan Leila, Teimoori Batool, Mehrabani Mehrnaz, Salimi Saeedeh

Abstract excerpt

The effect of DNA methylation on gene expression triggered it as a susceptibility factor in various diseases including preeclampsia (PE). The pathogenesis of PE is closely associated with the methylation status and genetic variants of relevant genes. Therefore, the aim of the study was to investigate the possible impacts of the placental DNA methylation and rs3741219, rs217727, and rs2107425 polymorphisms of the...

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PMID: 31769935
DOI: 10.1002/iub.2199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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