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Article

Tumor mutation burden, immune checkpoint crosstalk and radiosensitivity in single-cell RNA sequencing data of breast cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jan 2020

Jang Bum-Sup, Han Wonsik, Kim In Ah

Abstract excerpt

INTRODUCTION: We analyzed transcriptional and mutational profile mainly focused on tumor mutation burden (TMB), immune checkpoint crosstalk, and radiosensitivity using scRNA-seq data derived from breast cancer and immune cells. MATERIALS AND METHODS: scRNA-seq transcriptome data were acquired from the GEO database (GSE75688). The radiosensitivity index (RSI) was used to evaluate radiosensitivity of each cell....

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PMID: 31767471
DOI: 10.1016/j.radonc.2019.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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