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Article

[Analysis of the possible mechanisms for the persistence of the vaccinal strain of the measles virus in a human cell culture].

Voprosy virusologii - 1 Jan 2000

Andzhaparidze O G, Bogomolova N N, Boriskin Iu S, Koptiaeva I B, Chaplygina N M

Abstract excerpt

The mechanisms (factors) of the measles virus vaccine L-16 strain persistence in HEp-2 cell culture were analysed. Among the known mechanisms, most likely is the reduction of the cell-destroying properties of the persisting virus due to mutations in nucleoprotein gene manifested by changes of the...

Topics

Cells, Cultured
Cytopathogenic Effect, Viral
Defective Viruses
Humans
Measles virus
Mutation
Time Factors
Viral Interference
Viral Proteins
Virus Cultivation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 3176432

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3176432-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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