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Article

Low expression or hypermethylation of PLK2 might predict favorable prognosis for patients with glioblastoma multiforme

19 Nov 2019

Abstract excerpt

Background As the most aggressive brain tumor, patients with glioblastoma multiforme (GBM) have a poor prognosis. Our purpose was to explore prognostic value of Polo-like kinase 2 (PLK2) in GBM, a member of the PLKs family. Methods The expression profile of PLK2 in GBM was obtained from The Cancer Genome Atlas database. The PLK2 expression in GBM was tested. Kaplan–Meier curves were generated to assess the...

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PMID: 31763067
DOI: 10.7717/peerj.7974

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