Longitudinal study of the bacterial and fungal microbiota in the human sinuses reveals seasonal and annual changes in diversity

Abstract excerpt

There is a pressing need for longitudinal studies which examine the stability of the sinonasal microbiota. In this study, we investigated bacterial and fungal community composition of the sinuses of four healthy individuals every month for one year, then once every three months for an additional year to capture seasonal variation. Sequencing of bacterial 16S rRNA genes and fungal ITS2 revealed communities that...

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