Article
Clinical and genetic correlates of islet-autoimmune signatures in juvenile-onset type 1 diabetes.
Diabetologia - 1 Feb 2020
Claessens Laura A, Wesselius Joris, van Lummel Menno, Laban Sandra, Mulder Flip, Mul Dick, Nikolic Tanja, Aanstoot Henk-Jan, Koeleman Bobby P C, Roep Bart O
Abstract excerpt
AIMS/HYPOTHESIS: Heterogeneity in individuals with type 1 diabetes has become more generally appreciated, but has not yet been extensively and systematically characterised. Here, we aimed to characterise type 1 diabetes heterogeneity by creating immunological, genetic and clinical profiles for individuals with juvenile-onset type 1 diabetes in a cross-sectional study. METHODS: Participants were HLA-genotyped to...
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