Article
Biomarker concordance between molecular stereotactic biopsy and open surgical specimens in gliomas.
Neurologia i neurochirurgia polska - 1 Jan 2019
Furtak Jacek, Mielczarek Maciej, Szylberg Mateusz, Harat Maciej
Abstract excerpt
AIMS: To compare 1p/19q codeletion, MGMT promoter methylation, and IDH mutation status in stereotactic biopsy and open craniotomy specimens. CLINICAL RATIONALE: The latest WHO classification of gliomas requires assessment of the expression of molecular markers. Samples can be obtained for molecular assays via open craniotomy or molecular stereotactic biopsy (MSB). However, there is uncertainty as to whether MSB...
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