Article
Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients.
Acta neurochirurgica - 1 Aug 2014
Eigenbrod Sabina, Trabold Raimund, Brucker David, Erös Christian, Egensperger Rupert, La Fougere Christian, Göbel Werner, Rühm Adrian, Kretzschmar Hans A, Tonn Jörg C, Herms Jochen, Giese Armin, Kreth Friedrich W
Abstract excerpt
BACKGROUND: In gliomas molecular biomarkers are increasingly gaining diagnostic, prognostic and predictive significance. Determination of biomarker status after biopsy is important as not all patients are eligible for open tumor resection. We developed and validated prospectively (6/10-12/11) a protocol allowing for both reliable determination of multiple biomarkers and representative histological diagnoses from...
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