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Article

Proof of concept for identifying cystic fibrosis from perspiration samples.

Proceedings of the National Academy of Sciences of the United States of America - 3 Dec 2019

Zhou Zhenpeng, Alvarez Daniel, Milla Carlos, Zare Richard N

Abstract excerpt

The gold standard for cystic fibrosis (CF) diagnosis is the determination of chloride concentration in sweat. Current testing methodology takes up to 3 h to complete and has recognized shortcomings on its diagnostic accuracy. We present an alternative method for the identification of CF by combining desorption electrospray ionization mass spectrometry and a machine-learning algorithm based on gradient boosted...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 31740593
DOI: 10.1073/pnas.1909630116
PMCID: PMC6900510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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