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Immune evasion by adenoviruses: a window into host–virus adaptation

18 Nov 2019

Abstract excerpt

Human adenoviruses (HAdVs) are widespread pathogens that cause a number of partially overlapping, species-specific infections associated with respiratory, urinary, gastrointestinal, and ocular diseases. The early 3 (E3) region of adenoviruses is highly divergent between different species, and it encodes a multitude of proteins with immunomodulatory functions. The study of genetic diversity in the E3 region offers...

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PMID: 31736048
DOI: 10.1002/1873-3468.13682

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