Article
Adult Human Dermal Progenitor Cell Transplantation Modulates the Functional Outcome of Split-Thickness Skin Xenografts.
Stem cell reports - 10 Dec 2019
Agabalyan Natacha A, Sparks Holly D, Tarraf Samar, Rosin Nicole L, Anker Katie, Yoon Grace, Burnett Lindsay N, Nickerson Duncan, Di Martino Elena S, Gabriel Vincent A, Biernaskie Jeff
Abstract excerpt
Following full-thickness skin injuries, epithelialization of the wound is essential. The standard of care to achieve this wound "closure" in patients is autologous split-thickness skin grafting (STSG). However, patients living with STSGs report significant chronic impairments leading to functional deficiencies such as itch, altered sensation, fragility, hypertrophic scarring, and contractures. These features are...
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