Article
Associations of microRNAs, Angiogenesis-Regulating Factors and CFH Y402H Polymorphism-An Attempt to Search for Systemic Biomarkers in Age-Related Macular Degeneration.
International journal of molecular sciences - 15 Nov 2019
Ulańczyk Zofia, Sobuś Anna, Łuczkowska Karolina, Grabowicz Aleksandra, Mozolewska-Piotrowska Katarzyna, Safranow Krzysztof, Kawa Miłosz Piotr, Pałucha Andrzej, Krawczyk Mariusz, Sikora Piotr, Matczyńska Ewa, Machaliński Bogusław, Machalińska Anna
Abstract excerpt
Age-related macular degeneration (AMD) remains the leading cause of blindness in elderly people, but the pathophysiology of this disease is still largely unknown. We investigated the systemic expression of angiogenesis-regulating growth factors and selected miRNAs known to regulate angiogenesis in AMD patients. We also focused on possible correlations of their expression with the presence of CFH Y402H or ARMS...
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