Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice.

Science translational medicine - 13 Nov 2019

Kundu Parag, Lee Hae Ung, Garcia-Perez Isabel, Tay Emmy Xue Yun, Kim Hyejin, Faylon Llanto Elma, Martin Katherine A, Purbojati Rikky, Drautz-Moses Daniela I, Ghosh Sujoy, Nicholson Jeremy K, Schuster Stephan, Holmes Elaine, Pettersson Sven

Abstract excerpt

The gut microbiota evolves as the host ages, yet the effects of these microbial changes on host physiology and energy homeostasis are poorly understood. To investigate these potential effects, we transplanted the gut microbiota of old or young mice into young germ-free recipient mice. Both groups showed similar weight gain and skeletal muscle mass, but germ-free mice receiving a gut microbiota transplant from old...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Butyrates
Share to Doublecortin Domain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factors

Share to Germ-Free Life

Share to Metabolome

Share to Neurogenesis

Share to Neuropeptides

Share to Proton Magnetic Resonance Spectroscopy

Source

Identifiers

PMID: 31723038
DOI: 10.1126/scitranslmed.aau4760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice.PMID 31723038Read ↗

Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipientsSemantic proximity Read ↗

Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipientsSemantic proximity Read ↗

Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brainSemantic proximity Read ↗

The aging mouse microbiome has obesogenic characteristics.Semantic proximity Read ↗

Dynamics of Gut Microbiota Recovery after Antibiotic Exposure in Young and Old Mice (A Pilot Study)Semantic proximity Read ↗

Lactobacillus acidophilus DDS-1 Modulates the Gut Microbiota and Improves Metabolic Profiles in Aging Mice.Semantic proximity Read ↗

Fecal microbiota transplantation, a tool to transfer healthy longevitySemantic proximity Read ↗

Gut microbiota of the young ameliorates physical fitness of the aged in miceSemantic proximity Read ↗

Long-Term Blackcurrant Supplementation Modified Gut Microbiome Profiles in Mice in an Age-Dependent Manner: An Exploratory StudySemantic proximity Read ↗

Age and diet affect self-resilience of intestinal microbiome in miceSemantic proximity Read ↗

Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat dietSemantic proximity Read ↗

Disruption of the Circadian Rhythm Is Exacerbated by Aging and Ameliorated by Time- restricted FeedingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.