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Article

The aging mouse microbiome has obesogenic characteristics.

Genome medicine - 12 Oct 2020

Binyamin Dana, Werbner Nir, Nuriel-Ohayon Meital, Uzan Atara, Mor Hadar, Abbas Atallah, Ziv Oren, Teperino Raffaele, Gutman Roee, Koren Omry

Abstract excerpt

BACKGROUND: During aging, there is a physiological decline, an increase of morbidity and mortality, and a natural change in the gut microbiome. In this study, we investigated the influence of the gut microbiome on different metabolic parameters in adult and aged mice. METHODS: Fecal and blood samples from adult (n = 42, 100-300 days) and aging (n = 32, 550-750 days) mice were collected. Microbiome analysis was...

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Identifiers

PMID: 33046129
DOI: 10.1186/s13073-020-00784-9
PMCID: PMC7552538

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